Andersen's Disease is usally characterized by a lack of glycogen branching enzyme (GBE). As its name suggests, it exist to form multiple branch point during the formation of glycogen (which is what we want). Since we know that glucose is stored as glycogen which is essentially the branched form of glucose -plays flashback scene of MBC & Physiology lectures- , the lack of GBE leads to structurally abnormal glycogen!
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| So a glycogen with less branching point would look similar to amylopectin, which is the reason why Andersen's Disease is sometimes also known as Amylopectinosis. |
So what's how do doctors diagnose a patient with Andersen's Disease? That's for you to find out in another blog post!
Sources:
http://www.rarediseases.org/rare-disease-information/rare-diseases/byID/394/viewFullReport
http://2012books.lardbucket.org/books/an-introduction-to-nutrition/section_08/83d76e165d784a9bc705cc259e416ed9.jpg
What would happen if the glycogen looks similar to amylopectin? Would it become a functionality issue? (like would the body mistook glycogen as amylopectin and cause some problems in the body as a result?)
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